13–14 May 2018
Asia/Tehran timezone

FT-IR Microspectroscopy Evaluation of Wound Healing Potentials of Acid Soluble Collagen from Fish Scale and Glycoprotein Extract from Earthworm on Diabetic Rats using Synchrotron Radiation

Not scheduled
20m
Poster Presentation

Speaker

Dr Fatemeh Elmi (University of Mazandaran)

Description

Diabetes is considered as a major health problem. Diabetic patients suffer an impaired wound healing process might lead to ulcers. The earthworm Eisenia foetida glycolipoprotein (as known G-90) is a combination of macromolecules which can improve wound healing. Collagen type I is involved in all steps of the wound-healing process. This study was conducted to investigate the effect of G-90 and acid soluble collagen (ASC) extracted from fish scale on the wound healing process in diabetic rats by SR-FTIR µspectroscopy. Principal component analysis (PCA) is used to identify the most significant spectral changes. The PCA results of the fingerprint and lipid regions are distinctive for both G-90 and ASC treated samples than D-panthenol treated samples. The morphology results revealed that treatment by using G-90 as well as ASC can speed up the wound healing process.

Author

Dr Fatemeh Elmi (University of Mazandaran)

Co-authors

Dr Farideh Feizi (Babol University of Medical Sciences) Dr Maryam Mitra Elmi (Babol University of Medical Sciences)

Presentation materials

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