Speaker
Dr
Fatemeh Elmi
(University of Mazandaran)
Description
Diabetes is considered as a major health problem. Diabetic patients suffer an impaired wound healing process might lead to ulcers. The earthworm Eisenia foetida glycolipoprotein (as known G-90) is a combination of macromolecules which can improve wound healing. Collagen type I is involved in all steps of the wound-healing process. This study was conducted to investigate the effect of G-90 and acid soluble collagen (ASC) extracted from fish scale on the wound healing process in diabetic rats by SR-FTIR µspectroscopy. Principal component analysis (PCA) is used to identify the most significant spectral changes. The PCA results of the fingerprint and lipid regions are distinctive for both G-90 and ASC treated samples than D-panthenol treated samples. The morphology results revealed that treatment by using G-90 as well as ASC can speed up the wound healing process.
Author
Dr
Fatemeh Elmi
(University of Mazandaran)
Co-authors
Dr
Farideh Feizi
(Babol University of Medical Sciences)
Dr
Maryam Mitra Elmi
(Babol University of Medical Sciences)